Vivid Biology ltd is on pause until 2028 whilst Claudia is living in Madrid, Spain. Claudia is still taking on design work as a freelancer.
Stem cells in the brain: Glial identity and Niches
2015
Fiona Doetsch
Summary of the science
Stem cells in the brain, specifically a type called adult neural stem cells, are a fascinating area of research. These stem cells are a subset of glial cells, which are commonly known as support cells in the brain. Surprisingly, it's been discovered that certain glial cells may have the ability to transform into stem cells in different brain regions. These stem cells reside in specialised areas called niches, where they receive signals and support for their growth and development. Scientists are studying these niches and the factors that control the behaviour of these stem cells, hoping to unlock their potential for brain repair and regeneration.
About the research
Fiona Doetsch's lab focuses on studying adult neural stem cells in the adult mammalian brain to understand how they are regulated. These stem cells are a subset of glial cells and continuously produce new neurons that integrate into specific brain regions. They reside in specialised niches, responding to various signals for self-renewal and differentiation. Their research aims to uncover the molecular and cellular pathways underlying these processes, providing insights for future therapeutic approaches.
About the illustration
The adult neuronal stem cells projected onto a cross-section of the brain are there to suggest their importance in brain development. They are shown to grow develop into different shapes and extend as if to suggest they are in the process of producing new neurons.